CCDC33

Across TCGA cell cohorts, CCDC33 mutation is significantly associated with the RNA expression of many other genes, with 23 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCDC33-associated genes across cancer lineages are OR6J1, RBMY1A1, and RBMY1E. Each is linked with CCDC33 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC33-to-partner and partner-to-CCDC33 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR6J1 grouped by CCDC33-low versus CCDC33-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC33→partner) and Y-score (partner→CCDC33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR6J1 →	+0.040	+3.234	<.001	.008	3	2
BLOOD_Myeloma	RBMY1A1 →	+1.464	+4.285	<.001	.003	3	1
BLOOD_Myeloma	RBMY1E →	+0.792	+4.754	<.001	<.001	3	1
STOMACH	CT47A6 →	+0.046	+5.285	<.001	.003	3	1
BLOOD_Leukemia	PRM2 →	+0.027	+3.969	<.001	.009	3	1
BLOOD_Leukemia	CHIA →	+0.013	+3.475	.003	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

OR6J1 by CCDC33 expression — BLOOD_Leukemia

Explore this box plot interactively →