Across TCGA patient cohorts, CCDC30 mutation is significantly associated with the RNA expression of many other genes, with 2,811 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC30-associated genes across cancer lineages are RNU7-188P, MIR548AL, and MRPS11P1. Each is linked with CCDC30 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCDC30-to-partner and partner-to-CCDC30 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC30→partner) and Y-score (partner→CCDC30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU7-188P →	+0.418	+9.057	<.001	.003	3	3
LGG	MIR548AL →	+0.546	+5.266	<.001	.006	3	3
HNSC	MRPS11P1 →	+0.080	+5.578	<.001	.004	3	2
HNSC	PRAMEF28P →	+0.037	+5.578	<.001	.004	3	2
BRCA	RNU6-1108P →	+0.282	+7.731	<.001	.009	3	2
BRCA	RNA5SP287 →	+0.283	+8.471	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,811 associations by consensus.

Exploration

CCDC30 survival (RNA) · tumor vs normal (RNA) · all CCDC30 data types