CCDC3

Across TCGA patient cohorts, CCDC3 protein abundance is significantly associated with the RNA expression of many other genes, with 155 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CCDC3-associated genes across cancer lineages are RGCC, PKD2L1, and MTUS1. Each is linked with CCDC3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC3-to-partner and partner-to-CCDC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC3 versus RGCC in GBM, with a Pearson correlation of 0.90.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC3→partner) and Y-score (partner→CCDC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RGCC →	+1.556	+1.599	.006	.001	3	1
GBM	PKD2L1 →	+0.736	+1.516	.005	.008	3	1
GBM	MTUS1 →	+0.855	+1.139	.007	.004	3	1
GBM	DSC3 →	-0.383	-1.379	<.001	.007	3	1
GBM	HTR1B →	+0.323	+1.139	.006	.004	3	1
GBM	CXCL9 →	+1.761	+1.139	.007	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 155 associations by consensus.

CCDC3 vs RGCC — GBM

Explore this scatter interactively →