CCDC3

Across TCGA patient cohorts, CCDC3 protein abundance is significantly associated with the protein abundance of many other proteins, with 175 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CCDC3-associated proteins across cancer lineages are BNIP3L_S62, AFDN_S1455, and SNX19. Each is linked with CCDC3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC3-to-partner and partner-to-CCDC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC3 versus BNIP3L_S62 in GBM, with a Pearson correlation of 0.80.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC3→partner) and Y-score (partner→CCDC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	BNIP3L_S62 →	+0.437	+1.139	.004	.004	3	1
GBM	AFDN_S1455 →	-0.729	-1.599	<.001	.001	3	1
GBM	SNX19 →	+0.443	+1.786	<.001	<.001	3	1
GBM	NISCH_S51 →	-0.736	-1.599	.001	.001	3	1
GBM	ACIN1_S410 →	-0.408	-1.201	.004	.004	2	1
GBM	BAG6 →	-0.208	-1.101	.004	.008	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 175 associations by consensus.

CCDC3 vs BNIP3L_S62 — GBM

Explore this scatter interactively →