CCDC3

Across TCGA patient cohorts, CCDC3 mutation is significantly associated with the RNA expression of many other genes, with 451 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC3-associated genes across cancer lineages are OR52I2, GAS2L1, and TRBV24OR9-2. Each is linked with CCDC3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC3-to-partner and partner-to-CCDC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR52I2 grouped by CCDC3-low versus CCDC3-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC3→partner) and Y-score (partner→CCDC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	OR52I2 →	+0.050	+5.925	<.001	.002	3	2
UCEC	GAS2L1 →	+0.591	+3.584	.003	.003	3	2
UCEC	TRBV24OR9-2 →	+0.102	+3.386	<.001	.004	3	2
UCEC	RNU6-1064P →	+0.715	+2.909	<.001	<.001	3	2
UCEC	RN7SL317P →	+0.126	+2.456	.008	.006	3	2
READ	PGBD4P2 →	+0.162	+6.257	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 451 associations by consensus.

OR52I2 by CCDC3 expression — READ

Explore this box plot interactively →