CCDC28B

Across TCGA patient cohorts, CCDC28B protein abundance is significantly associated with the RNA expression of many other genes, with 1,120 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CCDC28B-associated genes across cancer lineages are EGFEM1P, AREG, and EVA1A. Each is linked with CCDC28B in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC28B-to-partner and partner-to-CCDC28B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC28B versus EGFEM1P in GBM, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC28B→partner) and Y-score (partner→CCDC28B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	EGFEM1P →	+1.317	+0.752	.001	.001	3	2
HNSC	AREG →	+1.718	+0.597	.003	.004	3	1
HNSC	EVA1A →	+2.073	+0.834	<.001	.001	3	1
HNSC	EPB41L4A →	-1.043	-0.576	.001	.004	3	1
HNSC	FAM117B →	-1.317	-0.565	.003	.004	3	1
HNSC	PRDM5 →	+1.149	+0.491	.004	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,120 associations by consensus.

CCDC28B vs EGFEM1P — GBM

Explore this scatter interactively →