CCDC28B

Across TCGA patient cohorts, CCDC28B mutation is significantly associated with the RNA expression of many other genes, with 1,718 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC28B-associated genes across cancer lineages are RN7SKP291, RN7SKP45, and RNU6-144P. Each is linked with CCDC28B in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC28B-to-partner and partner-to-CCDC28B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP291 grouped by CCDC28B-low versus CCDC28B-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC28B→partner) and Y-score (partner→CCDC28B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RN7SKP291 →	+0.946	+5.707	<.001	<.001	3	2
COAD	RN7SKP45 →	+0.327	+6.306	<.001	<.001	3	2
COAD	RNU6-144P →	+0.379	+4.962	<.001	.003	3	2
COAD	MIR605 →	+0.641	+5.332	<.001	.002	3	2
COAD	MIR545 →	+0.345	+5.557	<.001	.001	3	2
COAD	MIR548U →	+2.072	+6.132	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,718 associations by consensus.

RN7SKP291 by CCDC28B expression — COAD

Explore this box plot interactively →