CCDC28B

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CCDC28B mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC28B-associated genes across cancer lineages are Endothelial cells and Th2 cells. Each is linked with CCDC28B in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC28B-to-partner and partner-to-CCDC28B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endothelial cells grouped by CCDC28B-low versus CCDC28B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC28B→partner) and Y-score (partner→CCDC28B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECEndothelial cells →-0.044-3.161.015.01931
UCECTh2 cells →+0.248+2.459.004.02031
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Endothelial cells by CCDC28B expression — UCEC

Box plot of Endothelial cells in CCDC28B-low vs CCDC28B-high samples in UCEC.

Explore this box plot interactively →

Exploration