CCDC28B

Across TCGA cell cohorts, CCDC28B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,747 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CCDC28B-associated GO terms across cancer lineages are Purine ribonucleotide biosynthetic process, Ribonucleoside triphosphate biosynthetic process, and Purine nucleotide biosynthetic process. Each is linked with CCDC28B in more than 9 cancer types. Because this analysis shows association rather than direction, both CCDC28B-to-partner and partner-to-CCDC28B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Purine ribonucleotide biosynthetic process grouped by CCDC28B-low versus CCDC28B-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC28B→partner) and Y-score (partner→CCDC28B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Purine ribonucleotide biosynthetic process →	+0.092	+0.937	<.001	<.001	3	10
OVARY	Ribonucleoside triphosphate biosynthetic process →	+0.083	+1.458	<.001	<.001	3	10
OVARY	Purine nucleotide biosynthetic process →	+0.078	+1.368	<.001	.001	3	10
OVARY	Aerobic respiration →	+0.078	+1.379	.004	<.001	3	9
OVARY	Nucleoside triphosphate metabolic process →	+0.071	+1.672	<.001	<.001	3	9
LUNG_SCLC	Purine nucleoside triphosphate metabolic process →	+0.069	+1.254	.002	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,747 associations by consensus.

Purine ribonucleotide biosynthetic process by CCDC28B expression — BONE

Explore this box plot interactively →