CCDC27

Across TCGA cell cohorts, CCDC27 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,529 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CCDC27-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Regulation of translational initiation, and Regulation of myoblast fusion. Each is linked with CCDC27 in more than 8 cancer types. Because this analysis shows association rather than direction, both CCDC27-to-partner and partner-to-CCDC27 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by CCDC27-low versus CCDC27-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC27→partner) and Y-score (partner→CCDC27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Negative regulation of syncytium formation by plasma membrane fusion →	+0.094	+0.034	<.001	.001	3	9
OVARY	Regulation of translational initiation →	+0.067	+0.041	<.001	.005	3	9
OVARY	Regulation of myoblast fusion →	+0.085	+0.032	<.001	.002	2	9
OVARY	Negative regulation of myoblast fusion →	+0.095	+0.034	<.001	.001	3	8
OVARY	Regulation of syncytium formation by plasma membrane fusion →	+0.076	+0.029	<.001	.001	2	9
STOMACH	5S class rRNA transcription by RNA polymerase III →	+0.201	+0.059	<.001	.009	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,529 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by CCDC27 expression — OVARY

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