CCDC197

Across TCGA patient cohorts, CCDC197 mutation is significantly associated with the RNA expression of many other genes, with 617 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC197-associated genes across cancer lineages are MIR6803, RN7SL331P, and MIR3915. Each is linked with CCDC197 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC197-to-partner and partner-to-CCDC197 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6803 grouped by CCDC197-low versus CCDC197-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC197→partner) and Y-score (partner→CCDC197) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6803 →	+0.212	+5.019	<.001	.001	3	2
BRCA	RN7SL331P →	+0.144	+8.055	<.001	.007	3	1
BRCA	MIR3915 →	+0.317	+7.731	<.001	.009	3	1
BRCA	MIR4287 →	+0.431	+7.731	<.001	.009	3	1
UCEC	GNPNAT1 →	+1.051	+3.595	<.001	.001	3	1
UCEC	CDADC1 →	+0.450	+3.499	.003	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 617 associations by consensus.

MIR6803 by CCDC197 expression — UCEC

Explore this box plot interactively →