CCDC197

Across TCGA pan-cancer cohorts, CCDC197 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of CCDC197’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where CCDC197 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CCDC197 is over-expressed in tumor, although a few such as PAAD and HNSC show the opposite, repressed pattern.

KIRP, KIRC, and THCA are the cancer types where CCDC197 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CCDC197 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	All	III,IV	+0.230	.002	6	view →
KIRC	All	All	+0.020	.017	5	view →
THCA	All	All	+0.019	.011	5	view →
PAAD	Female	All	−0.055	.008	4	view →
UCEC	All	IV	+0.285	.035	2	view →
HNSC	Male	IV	−0.171	.045	1	view →
LIHC	Female	All	+0.010	.015	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

CCDC197–KIRP

Open the KIRP breakdown →