CCDC191

Across TCGA cell cohorts, CCDC191 mutation is significantly associated with the RNA expression of many other genes, with 565 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCDC191-associated genes across cancer lineages are PRSS50, DYDC1, and GALP. Each is linked with CCDC191 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC191-to-partner and partner-to-CCDC191 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRSS50 grouped by CCDC191-low versus CCDC191-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC191→partner) and Y-score (partner→CCDC191) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	PRSS50 →	+0.031	+3.388	<.001	.002	3	2
URINARY_TRACT	DYDC1 →	+0.073	+5.087	<.001	.004	3	1
URINARY_TRACT	GALP →	+0.036	+5.087	<.001	.004	3	1
BLOOD_Lymphoma	PCARE →	+0.030	+3.523	<.001	.009	3	1
BLOOD_Lymphoma	OR5T2 →	+0.004	+4.662	<.001	.003	3	1
BLOOD_Lymphoma	DPEP2NB →	+0.050	+3.745	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 565 associations by consensus.

PRSS50 by CCDC191 expression — BLOOD_Leukemia

Explore this box plot interactively →