CCDC186

Across TCGA patient cohorts, CCDC186 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,270 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CCDC186-associated proteins across cancer lineages are SLK, NHLRC2, and ABLIM1. Each is linked with CCDC186 in more than 6 cancer types. Because this analysis shows association rather than direction, both CCDC186-to-partner and partner-to-CCDC186 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC186 versus SLK in UCEC, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC186→partner) and Y-score (partner→CCDC186) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SLK →	+0.383	+0.555	<.001	<.001	3	7
GBM	NHLRC2 →	+0.285	+0.506	<.001	<.001	3	6
BRCA	ABLIM1 →	+0.545	+0.660	<.001	<.001	3	6
BRCA	ATE1 →	+0.332	+0.779	<.001	<.001	3	5
BRCA	EIF4EBP2 →	+0.303	+0.555	<.001	.008	3	5
BRCA	POLR1A →	-0.291	-0.639	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,270 associations by consensus.

CCDC186 vs SLK — UCEC

Explore this scatter interactively →