CCDC186

Across TCGA patient cohorts, CCDC186 protein abundance is significantly associated with the RNA expression of many other genes, with 13,758 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CCDC186-associated genes across cancer lineages are VWA2, DHX32, and CASP7. Each is linked with CCDC186 in more than 5 cancer types. Because this analysis shows association rather than direction, both CCDC186-to-partner and partner-to-CCDC186 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC186 versus VWA2 in COAD, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC186→partner) and Y-score (partner→CCDC186) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	VWA2 →	+1.363	+0.325	<.001	.002	3	6
UCEC	DHX32 →	+0.912	+0.376	<.001	<.001	3	6
UCEC	CASP7 →	+0.567	+0.248	<.001	<.001	3	5
UCEC	TSPAN15 →	+0.742	+0.264	.005	.003	3	5
LSCC	SEMA6D →	-1.700	-0.295	<.001	<.001	3	5
HNSC	PDZK1IP1 →	+1.382	+0.195	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,758 associations by consensus.

CCDC186 vs VWA2 — COAD

Explore this scatter interactively →