CCDC186

Across TCGA cell cohorts, CCDC186 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,790 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCDC186-associated GO terms across cancer lineages are Protein modification by small protein removal, Golgi vesicle transport, and Protein localization to vacuole. Each is linked with CCDC186 in more than 16 cancer types. Because this analysis shows association rather than direction, both CCDC186-to-partner and partner-to-CCDC186 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein modification by small protein removal grouped by CCDC186-low versus CCDC186-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC186→partner) and Y-score (partner→CCDC186) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Protein modification by small protein removal →	+0.054	+1.026	<.001	<.001	3	17
LUNG_SCLC	Golgi vesicle transport →	+0.072	+1.287	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Protein localization to vacuole →	+0.099	+1.299	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Establishment of protein localization to vacuole →	+0.091	+1.206	<.001	<.001	3	16
STOMACH	Golgi vesicle budding →	+0.175	+1.366	<.001	.002	3	16
UPPER_AERODIGESTIVE_TRACT	Vesicle-mediated transport to the plasma membrane →	+0.084	+1.125	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,790 associations by consensus.

Protein modification by small protein removal by CCDC186 expression — OVARY

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