CCDC185

Across TCGA patient cohorts, CCDC185 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,073 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CCDC185-associated GO terms across cancer lineages are Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), Regulation of dendritic spine development, and Microtubule polymerization. Each is linked with CCDC185 in more than 16 cancer types. Because this analysis shows association rather than direction, both CCDC185-to-partner and partner-to-CCDC185 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) grouped by CCDC185-low versus CCDC185-high in UCS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC185→partner) and Y-score (partner→CCDC185) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCS	Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.058	+0.324	<.001	.002	2	17
UCS	Regulation of dendritic spine development →	+0.029	+0.388	.002	.002	3	15
ESCA	Microtubule polymerization →	+0.046	+0.268	.001	<.001	3	15
ESCA	Transcription by RNA polymerase I →	+0.048	+0.174	<.001	.001	2	16
STAD	Receptor recycling →	+0.039	+0.073	<.001	<.001	3	15
STAD	Receptor metabolic process →	+0.040	+0.083	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,073 associations by consensus.

Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) by CCDC185 expression — UCS

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