CCDC185

Across TCGA patient cohorts, CCDC185 mutation is significantly associated with the RNA expression of many other genes, with 2,609 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC185-associated genes across cancer lineages are BNIP3P4, MIR3153, and LRRC37A16P. Each is linked with CCDC185 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC185-to-partner and partner-to-CCDC185 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BNIP3P4 grouped by CCDC185-low versus CCDC185-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC185→partner) and Y-score (partner→CCDC185) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	BNIP3P4 →	+0.060	+5.479	<.001	.002	3	2
UCEC	MIR3153 →	+0.859	+2.671	<.001	.001	3	2
UCEC	LRRC37A16P →	+0.569	+2.098	.001	.003	3	2
UCEC	ZNF587B →	+0.392	+2.098	.006	.003	3	2
UCEC	BIVM-ERCC5 →	+0.009	+2.163	<.001	.002	3	2
HNSC	MIR128-1 →	+0.472	+5.912	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,609 associations by consensus.

BNIP3P4 by CCDC185 expression — LIHC

Explore this box plot interactively →