CCDC178

Across TCGA cell cohorts, CCDC178 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,461 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible CCDC178-associated GO terms across cancer lineages are Cell-matrix adhesion, Substrate adhesion-dependent cell spreading, and Positive regulation of myoblast fusion. Each is linked with CCDC178 in more than 4 cancer types. Because this analysis shows association rather than direction, both CCDC178-to-partner and partner-to-CCDC178 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell-matrix adhesion grouped by CCDC178-low versus CCDC178-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC178→partner) and Y-score (partner→CCDC178) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Cell-matrix adhesion →	-0.058	-0.744	.003	.007	3	5
LUNG_SCLC	Substrate adhesion-dependent cell spreading →	-0.147	-1.075	<.001	<.001	3	5
SKIN	Positive regulation of myoblast fusion →	-0.132	-0.079	.001	.006	3	4
SOFT_TISSUE	Membrane repolarization →	-0.152	-0.595	<.001	.008	3	4
OVARY	Cellular response to mechanical stimulus →	-0.062	-0.625	<.001	.007	3	4
BLOOD_Lymphoma	Neuroblast differentiation →	+0.878	+0.330	<.001	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,461 associations by consensus.

Cell-matrix adhesion by CCDC178 expression — SOFT_TISSUE

Explore this box plot interactively →