CCDC177

Across TCGA patient cohorts, CCDC177 protein abundance is significantly associated with the RNA expression of many other genes, with 3,378 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CCDC177-associated genes across cancer lineages are B3GAT1, FOLH1B, and GLT1D1. Each is linked with CCDC177 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC177-to-partner and partner-to-CCDC177 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC177 versus B3GAT1 in GBM, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC177→partner) and Y-score (partner→CCDC177) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	B3GAT1 →	+0.895	+0.462	.001	<.001	3	2
BRCA	FOLH1B →	+0.721	+0.964	.009	.004	3	2
GBM	GLT1D1 →	+1.080	+0.665	<.001	<.001	3	2
BRCA	FBXO41 →	+0.627	+0.964	<.001	.004	3	2
GBM	ACSL6 →	+0.689	+0.454	<.001	<.001	3	2
GBM	ATCAY →	+1.327	+0.394	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,378 associations by consensus.

CCDC177 vs B3GAT1 — GBM

Explore this scatter interactively →