CCDC177

Across TCGA patient cohorts, CCDC177 protein abundance is significantly associated with the protein abundance of many other proteins, with 11,855 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CCDC177-associated proteins across cancer lineages are S1PR1_S351, SHANK3, and STK32C_S18. Each is linked with CCDC177 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC177-to-partner and partner-to-CCDC177 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC177 versus S1PR1_S351 in GBM, with a Pearson correlation of 0.49.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC177→partner) and Y-score (partner→CCDC177) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	S1PR1_S351 →	+0.535	+0.488	<.001	<.001	3	2
GBM	SHANK3 →	+0.566	+0.580	<.001	<.001	3	2
BRCA	STK32C_S18 →	+0.928	+0.964	.002	.004	3	2
GBM	TAMALIN_S94 →	+0.706	+0.665	<.001	<.001	3	2
BRCA	CCDC92 →	+0.665	+0.964	.004	.004	3	2
GBM	FAM117B_S10 →	+0.355	+0.420	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,855 associations by consensus.

CCDC177 vs S1PR1_S351 — GBM

Explore this scatter interactively →