CCDC173

Across TCGA cell cohorts, CCDC173 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCDC173-associated genes across cancer lineages are MCHR2, R3HDML, and HHLA1. Each is linked with CCDC173 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC173-to-partner and partner-to-CCDC173 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MCHR2 grouped by CCDC173-low versus CCDC173-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC173→partner) and Y-score (partner→CCDC173) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MCHR2 →	+0.034	+4.539	<.001	.007	3	2
BLOOD_Leukemia	R3HDML →	+0.020	+5.569	<.001	.001	3	1
BLOOD_Leukemia	HHLA1 →	+0.011	+4.551	<.001	.004	3	1
BLOOD_Leukemia	ABCG8 →	+0.021	+4.152	<.001	.009	3	1
BLOOD_Leukemia	OR56A1 →	+0.069	+4.276	<.001	.007	3	1
BLOOD_Leukemia	KRT40 →	+0.017	+4.152	.002	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

MCHR2 by CCDC173 expression — BLOOD_Leukemia

Explore this box plot interactively →