CCDC173

Across TCGA pan-cancer cohorts, CCDC173 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of CCDC173’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where CCDC173 RNA is repressed in tumor relative to normal tissue. In most cancer types CCDC173 is over-expressed in tumor, although a few such as LUAD and KICH show the opposite, repressed pattern.

LUAD, KICH, and THCA are the cancer types where CCDC173 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CCDC173 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	III,IV	−1.593	<.001	11	view →
KICH	Female	II,III,IV	−1.472	<.001	11	view →
THCA	Male	III,IV	−1.438	<.001	11	view →
LUSC	Female	II,III,IV	−1.947	<.001	8	view →
BLCA	All	III,IV	−0.318	.018	6	view →
BRCA	All	IV	−1.140	.046	2	view →
CHOL	Male	All	+0.768	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

CCDC173–LUAD

Open the LUAD breakdown →