CCDC171

Across TCGA patient cohorts, CCDC171 protein abundance is significantly associated with the RNA expression of many other genes, with 618 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC171-associated genes across cancer lineages are CXCR1, CXCR2, and RPS6KA5. Each is linked with CCDC171 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC171-to-partner and partner-to-CCDC171 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC171 versus CXCR1 in UCEC, with a Pearson correlation of 0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC171→partner) and Y-score (partner→CCDC171) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CXCR1 →	+1.182	+0.909	<.001	<.001	3	2
GBM	CXCR2 →	+1.114	+0.890	<.001	.003	3	2
UCEC	RPS6KA5 →	-1.098	-0.683	.007	.007	3	1
UCEC	PLCB4 →	-0.878	-0.943	<.001	<.001	3	1
UCEC	SUPT20H →	-0.490	-0.751	.002	.005	3	1
UCEC	NOMO3 →	+0.433	+0.529	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 618 associations by consensus.

CCDC171 vs CXCR1 — UCEC

Explore this scatter interactively →