CCDC171

Across TCGA pan-cancer cohorts, CCDC171 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of CCDC171’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where CCDC171 RNA is repressed in tumor relative to normal tissue. In most cancer types CCDC171 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KICH, THCA, and KIRC are the cancer types where CCDC171 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CCDC171 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	II,III,IV	−0.684	<.001	10	view →
THCA	Male	II,III,IV	−0.467	<.001	10	view →
KIRC	All	II,III,IV	−0.213	<.001	9	view →
LIHC	Female	II,III,IV	+0.148	<.001	5	view →
BLCA	Female	III,IV	+0.305	.019	3	view →
CHOL	All	All	+0.263	<.001	3	view →
UCEC	All	All	−0.568	.003	2	view →
LUSC	All	III,IV	−0.368	.003	2	view →
KIRP	Male	All	−0.255	.001	2	view →
LUAD	Female	II,III,IV	−0.170	.042	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

CCDC171–KICH

Open the KICH breakdown →