CCDC171

Across TCGA patient cohorts, CCDC171 mutation is significantly associated with the RNA expression of many other genes, with 2,847 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC171-associated genes across cancer lineages are ZNF79, KIR2DL4, and TRIB3. Each is linked with CCDC171 in more than 3 cancer types. Because this analysis shows association rather than direction, both CCDC171-to-partner and partner-to-CCDC171 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF79 grouped by CCDC171-low versus CCDC171-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC171→partner) and Y-score (partner→CCDC171) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZNF79 →	+0.334	+2.158	<.001	<.001	3	4
COAD	KIR2DL4 →	+0.475	+3.209	.003	.009	3	3
UCEC	TRIB3 →	+0.552	+2.087	.007	.005	3	3
UCEC	KCTD9 →	+0.475	+1.513	<.001	<.001	3	3
UCEC	UBAC1 →	+0.270	+1.599	.001	<.001	3	3
UCEC	MED18 →	+0.334	+2.070	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,847 associations by consensus.

ZNF79 by CCDC171 expression — UCEC

Explore this box plot interactively →