CCDC171

Across TCGA cell cohorts, CCDC171 mutation is significantly associated with the RNA expression of many other genes, with 248 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCDC171-associated genes across cancer lineages are DNAAF6, PAX4, and TNP1. Each is linked with CCDC171 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC171-to-partner and partner-to-CCDC171 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNAAF6 grouped by CCDC171-low versus CCDC171-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC171→partner) and Y-score (partner→CCDC171) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	DNAAF6 →	+0.040	+4.015	<.001	.002	3	2
SOFT_TISSUE	PAX4 →	+0.022	+4.930	<.001	.008	3	1
SOFT_TISSUE	TNP1 →	+1.481	+5.369	<.001	.004	3	1
SOFT_TISSUE	PGLYRP4 →	+0.016	+5.369	<.001	.004	3	1
SOFT_TISSUE	RLN3 →	+0.041	+5.369	<.001	.004	3	1
SOFT_TISSUE	FOXI2 →	+0.006	+4.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 248 associations by consensus.

DNAAF6 by CCDC171 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →