CCDC170

Across TCGA patient cohorts, CCDC170 protein abundance is significantly associated with the protein abundance of many other proteins, with 8,570 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CCDC170-associated proteins across cancer lineages are SPATA18_S507, IFT140, and RRM2. Each is linked with CCDC170 in more than 4 cancer types. Because this analysis shows association rather than direction, both CCDC170-to-partner and partner-to-CCDC170 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC170 versus SPATA18_S507 in UCEC, with a Pearson correlation of 0.74.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC170→partner) and Y-score (partner→CCDC170) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SPATA18_S507 →	+1.202	+1.119	<.001	<.001	3	5
BRCA	IFT140 →	+0.637	+0.979	<.001	<.001	3	5
UCEC	RRM2 →	-0.618	-0.685	<.001	<.001	3	4
UCEC	RSPH1_S297 →	+0.937	+1.200	<.001	<.001	3	4
UCEC	SPATA18 →	+1.500	+1.157	<.001	<.001	3	4
UCEC	SPATA6 →	+0.940	+1.067	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,570 associations by consensus.

CCDC170 vs SPATA18_S507 — UCEC

Explore this scatter interactively →