CCDC17

Across TCGA cell cohorts, CCDC17 mutation is significantly associated with the RNA expression of many other genes, with 23 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCDC17-associated genes across cancer lineages are SLC25A31, DTHD1, and GUCA1C. Each is linked with CCDC17 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC17-to-partner and partner-to-CCDC17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC25A31 grouped by CCDC17-low versus CCDC17-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC17→partner) and Y-score (partner→CCDC17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SLC25A31 →	+0.044	+3.115	.002	.004	3	2
URINARY_TRACT	DTHD1 →	+0.056	+5.087	<.001	.004	3	1
BLOOD_Leukemia	GUCA1C →	+0.023	+4.384	<.001	.006	3	1
BLOOD_Leukemia	OR51G2 →	+0.017	+4.384	<.001	.006	3	1
BLOOD_Leukemia	PIGY →	+1.750	+3.551	<.001	.009	3	1
BLOOD_Leukemia	MYH13 →	+0.762	+3.705	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

SLC25A31 by CCDC17 expression — LARGE_INTESTINE

Explore this box plot interactively →