CCDC163

Across TCGA patient cohorts, CCDC163 mutation is significantly associated with the RNA expression of many other genes, with 77 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC163-associated genes across cancer lineages are CCL27, RNA5SP76, and RNA5SP509. Each is linked with CCDC163 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC163-to-partner and partner-to-CCDC163 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCL27 grouped by CCDC163-low versus CCDC163-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC163→partner) and Y-score (partner→CCDC163) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CCL27 →	+0.056	+4.885	<.001	.002	3	2
BRCA	RNA5SP76 →	+0.339	+7.731	<.001	.009	3	1
LUSC	RNA5SP509 →	+0.413	+7.924	<.001	.008	3	1
LUSC	RNU6-1022P →	+0.458	+7.924	<.001	.008	3	1
LUSC	RNU6-499P →	+0.257	+7.924	<.001	.008	3	1
LUSC	LINC00266-4P →	+0.024	+7.924	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 77 associations by consensus.

CCL27 by CCDC163 expression — UCEC

Explore this box plot interactively →