Q-omics provides the consensus-scored RNU6-499P profile across patient tissues and cancer cell-line models. RNU6-499P expression is associated with patient survival in 11 of 34 cancer types, with the highest sampling consensus in COAD. Additionally, RNU6-499P RNA expression shows 8,948 significant gene co-expression associations, with the highest sampling consensus in LUSC. Together, these results highlight COAD, and LUSC as cancer lineages where RNU6-499P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes RNU6-499P survival associations across molecular data types. RNU6-499P RNA expression shows survival associations in the most cancer types (11). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

RNU6-499P data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	11	COAD (54)	view →

This table ranks reproducible RNU6-499P RNA expression–survival associations across cancer types. High RNU6-499P expression shows unfavorable associations in COAD, STAD, SKCM, ESCA, DLBC and BLCA. The COAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify COAD as the clearest survival context for RNU6-499P RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Tertile	II,III,IV	0.133	0.850	<.001	54	view →
STAD	OS	Tertile	II,III,IV	0.148	0.574	.002	45	view →
SKCM	OS	Tertile	All	0.202	0.781	<.001	45	view →
ESCA	OS	Tertile	II,III,IV	0.374	0.711	.007	36	view →
DLBC	OS	Tertile	III,IV	0.175	0.874	.025	36	view →
BLCA	DFS	Tertile	All	0.159	0.625	.016	27	view →

Pink = unfavorable, green = favorable. all 11 lineages →

RNU6-499P-COAD (OS)

Kaplan–Meier survival curve for RNU6-499P RNA expression in COAD: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with RNU6-499P in patient tissues and cancer cell lines. In patient samples, RNU6-499P shows the broadest associations at the RNA and protein expression levels, with LUSC recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	8,948	LUSC (4356)	view →
Function (RNA)	4,840	STAD (4756)	view →