CCDC153

Across TCGA cell cohorts, CCDC153 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCDC153-associated genes across cancer lineages are F9, WFDC12, and TACR3. Each is linked with CCDC153 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC153-to-partner and partner-to-CCDC153 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, F9 grouped by CCDC153-low versus CCDC153-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC153→partner) and Y-score (partner→CCDC153) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	F9 →	+0.009	+3.969	<.001	.009	3	1
BLOOD_Leukemia	WFDC12 →	+0.163	+3.289	<.001	.009	3	1
BLOOD_Leukemia	TACR3 →	+0.023	+3.475	<.001	.006	3	1
BLOOD_Leukemia	DEFB4A →	+0.106	+4.684	<.001	<.001	3	1
BLOOD_Leukemia	DIRC1 →	+0.024	+3.969	<.001	.009	3	1
BLOOD_Leukemia	TRIM49B →	+0.092	+3.289	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

F9 by CCDC153 expression — BLOOD_Leukemia

Explore this box plot interactively →