Across TCGA patient cohorts, CCDC152 mutation is significantly associated with the total protein of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC152-associated genes across cancer lineages are EGFR_pY1068, ACC1, and p62 Lck ligand. Each is linked with CCDC152 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC152-to-partner and partner-to-CCDC152 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC152→partner) and Y-score (partner→CCDC152) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.251	-2.700	.026	.006	3	1
UCEC	ACC1 →	+0.362	+2.820	.027	.035	3	1
UCEC	p62 Lck ligand →	+0.485	+2.700	<.001	.006	3	1
UCEC	Annexin-1 →	+0.596	+2.000	.012	.032	3	1
UCEC	Caspase-8 →	-0.324	-3.432	.004	.005	3	1
UCEC	CD49b →	-0.281	-3.302	.028	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration

CCDC152 survival (RNA) · tumor vs normal (RNA) · all CCDC152 data types