CCDC148

Across TCGA cell cohorts, CCDC148 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCDC148-associated genes across cancer lineages are OR10V1, CHIA, and BMP3. Each is linked with CCDC148 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC148-to-partner and partner-to-CCDC148 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10V1 grouped by CCDC148-low versus CCDC148-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC148→partner) and Y-score (partner→CCDC148) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR10V1 →	+0.035	+5.569	<.001	.001	3	2
LARGE_INTESTINE	CHIA →	+0.035	+3.345	<.001	.001	3	1
LARGE_INTESTINE	BMP3 →	+0.365	+3.839	.008	.001	3	1
LARGE_INTESTINE	TBC1D3 →	+0.043	+2.688	.007	.008	3	1
BLOOD_Leukemia	LRRC74A →	+0.049	+4.551	<.001	.004	3	1
BLOOD_Leukemia	HTR3D →	+0.014	+4.539	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

OR10V1 by CCDC148 expression — BLOOD_Leukemia

Explore this box plot interactively →