Across TCGA pan-cancer cohorts, CCDC144NL Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated CCDC144NL data layer compared with 21 for mass-spec protein.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher CCDC144NL Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CCDC144NL expression acts as an unfavorable survival marker.

BRCA, UCEC, and ACC are the cancer types where CCDC144NL Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Median	All	0.573	0.924	<.001	35	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
ACC	DFS	Median	All	0.195	0.748	.003	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: CCDC144NL tumor-vs-normal RNA expression · all CCDC144NL data types