Across TCGA pan-cancer cohorts, CCDC144NL RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of CCDC144NL’s most consistent transcriptional readouts.
The strongest signal is observed in kidney chromophobe (KICH), where CCDC144NL RNA is repressed in tumor relative to normal tissue. In most cancer types CCDC144NL is over-expressed in tumor, although a few such as KICH and UCEC show the opposite, repressed pattern.
KICH, UCEC, and HNSC are the cancer types where CCDC144NL tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CCDC144NL RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.