Across TCGA patient cohorts, CCDC144NL mutation is significantly associated with the total protein of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC144NL-associated genes across cancer lineages are 14-3-3_beta, GSK-3a-b_pS21_S9, and p27_pT157. Each is linked with CCDC144NL in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC144NL-to-partner and partner-to-CCDC144NL results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC144NL→partner) and Y-score (partner→CCDC144NL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	14-3-3_beta →	-0.106	-1.794	.010	.027	3	1
UCEC	GSK-3a-b_pS21_S9 →	+0.430	+2.331	.014	.019	3	1
UCEC	p27_pT157 →	-0.051	-2.308	.032	.033	3	1
UCEC	Akt_pS473 →	+0.733	+2.584	.012	.010	3	1
UCEC	PRAS40_pT246 →	+0.155	+1.820	.028	.016	3	1
UCEC	Rab25 →	-0.299	-3.169	.028	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

Exploration

CCDC144NL survival (RNA) · tumor vs normal (RNA) · all CCDC144NL data types