CCDC144NL-AS1

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CCDC144NL-AS1 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated CCDC144NL-AS1 data layer compared with 19 for mass-spec protein.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher CCDC144NL-AS1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CCDC144NL-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

LUSC, LUAD, and SKCM are the cancer types where CCDC144NL-AS1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUSCOSMedianAll0.1520.762.00112view →
LUADOSMedianAll0.2580.787.0276view →
SKCMDFSMedianAll0.2670.640.0473view →
UCECDFSMedianAll1.0000.626.0472view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

CCDC144NL-AS1–LUSC (OS)

Kaplan–Meier survival curve for CCDC144NL-AS1 mutant vs wild-type samples in LUSC.

Open the LUSC breakdown →

Exploration