CCDC144NL-AS1

Across TCGA pan-cancer cohorts, CCDC144NL-AS1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of CCDC144NL-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where CCDC144NL-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CCDC144NL-AS1 is over-expressed in tumor, although a few such as KICH and UCEC show the opposite, repressed pattern.

COAD, KICH, and KIRC are the cancer types where CCDC144NL-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CCDC144NL-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	+0.258	<.001	9	view →
KICH	All	All	−0.280	<.001	7	view →
KIRC	Male	All	+0.147	.001	7	view →
UCEC	All	All	−1.859	<.001	6	view →
HNSC	All	All	+0.313	.004	6	view →
LUAD	Female	II,III,IV	−0.426	.002	5	view →
LIHC	All	All	+0.374	.002	4	view →
STAD	All	All	+0.289	.002	4	view →
LUSC	Female	All	−0.404	.004	3	view →
BLCA	Female	All	+1.016	.040	2	view →
CHOL	All	All	+0.261	.006	2	view →
BLCA	Male	IV	−0.252	.015	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 11 lineages.

CCDC144NL-AS1–COAD

Open the COAD breakdown →