CCDC141

Across TCGA patient cohorts, CCDC141 protein abundance is significantly associated with the RNA expression of many other genes, with 7,231 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CCDC141-associated genes across cancer lineages are SRRM3, AMMECR1, and PHF7. Each is linked with CCDC141 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCDC141-to-partner and partner-to-CCDC141 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC141 versus SRRM3 in LSCC, with a Pearson correlation of -0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC141→partner) and Y-score (partner→CCDC141) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SRRM3 →	-0.533	-0.287	.001	.001	3	3
LSCC	AMMECR1 →	-0.558	-0.326	.005	.003	3	2
LSCC	PHF7 →	-0.366	-0.389	<.001	<.001	3	2
LSCC	ZNF500 →	-0.352	-0.389	<.001	.003	3	2
PDAC	MEFV →	+0.766	+1.690	<.001	<.001	3	2
LSCC	ZNF174 →	-0.333	-0.308	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,231 associations by consensus.

CCDC141 vs SRRM3 — LSCC

Explore this scatter interactively →