CCDC141

Across TCGA cell cohorts, CCDC141 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,365 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CCDC141-associated GO terms across cancer lineages are Mitotic cell cycle phase transition, Meiotic sister chromatid cohesion, centromeric, and DNA replication-dependent chromatin disassembly. Each is linked with CCDC141 in more than 4 cancer types. Because this analysis shows association rather than direction, both CCDC141-to-partner and partner-to-CCDC141 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic cell cycle phase transition grouped by CCDC141-low versus CCDC141-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC141→partner) and Y-score (partner→CCDC141) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Mitotic cell cycle phase transition →	+0.059	+0.874	<.001	.003	3	5
BLOOD_Myeloma	Meiotic sister chromatid cohesion, centromeric →	+0.102	+0.623	.002	.006	3	5
SOFT_TISSUE	DNA replication-dependent chromatin disassembly →	+0.109	+1.229	<.001	<.001	3	5
SOFT_TISSUE	Protein deubiquitination →	+0.048	+0.962	<.001	.007	3	5
SOFT_TISSUE	Regulation of binding of sperm to zona pellucida →	-0.741	-0.960	.004	.001	3	5
SOFT_TISSUE	Regulation of nucleotide-excision repair →	+0.058	+0.818	.005	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,365 associations by consensus.

Mitotic cell cycle phase transition by CCDC141 expression — SOFT_TISSUE

Explore this box plot interactively →