CCDC140

Across TCGA cell cohorts, CCDC140 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,060 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CCDC140-associated GO terms across cancer lineages are Cellular respiration, Aerobic respiration, and Regulation of protein localization to cilium. Each is linked with CCDC140 in more than 3 cancer types. Because this analysis shows association rather than direction, both CCDC140-to-partner and partner-to-CCDC140 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular respiration grouped by CCDC140-low versus CCDC140-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC140→partner) and Y-score (partner→CCDC140) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Cellular respiration →	+0.086	+0.345	<.001	<.001	3	4
SKIN	Aerobic respiration →	+0.099	+0.464	<.001	<.001	3	4
SKIN	Regulation of protein localization to cilium →	+0.058	+0.325	.001	<.001	3	4
SKIN	Chondroitin sulfate proteoglycan catabolic process →	+0.151	+0.338	<.001	<.001	3	3
SKIN	Hyperosmotic salinity response →	+0.080	+0.312	.002	<.001	3	3
SKIN	Positive regulation of smoothened signaling pathway →	+0.082	+0.498	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,060 associations by consensus.

Cellular respiration by CCDC140 expression — SKIN

Explore this box plot interactively →