Across TCGA pan-cancer cohorts, CCDC137 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CCDC137 data layer compared with 23 for mass-spec protein.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher CCDC137 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated CCDC137 expression acts as an unfavorable survival marker, although some lineages such as LSCC and UCEC show a favorable association.

PDAC, LSCC, and UCEC are the cancer types where CCDC137 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Quartile	All	0.243	0.581	.002	32	view →
LSCC	DFS	Tertile	II,III,IV	0.919	0.594	.007	16	view →
UCEC	DFS	Median	All	1.000	0.932	.023	10	view →
HNSC	DFS	Median	IV	0.328	0.889	.024	2	view →
GBM	OS	Median	All	0.551	0.356	.038	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: CCDC137 tumor-vs-normal RNA expression · all CCDC137 data types