CCDC136

Across TCGA patient cohorts, CCDC136 protein abundance is significantly associated with the RNA expression of many other genes, with 2,073 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CCDC136-associated genes across cancer lineages are PIK3IP1, SOX10, and SUN2. Each is linked with CCDC136 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC136-to-partner and partner-to-CCDC136 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC136 versus PIK3IP1 in GBM, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC136→partner) and Y-score (partner→CCDC136) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PIK3IP1 →	+0.517	+0.346	<.001	<.001	3	1
GBM	SOX10 →	+1.423	+0.418	.001	<.001	3	1
GBM	SUN2 →	+0.458	+0.444	<.001	<.001	3	1
GBM	RASL10A →	+0.719	+0.409	.001	<.001	3	1
GBM	NEFH →	+1.033	+0.336	<.001	<.001	3	1
GBM	RASD2 →	+0.682	+0.567	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,073 associations by consensus.

CCDC136 vs PIK3IP1 — GBM

Explore this scatter interactively →