CCDC136

Across TCGA cell cohorts, CCDC136 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,063 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCDC136-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Heterochromatin formation, and Epigenetic regulation of gene expression. Each is linked with CCDC136 in more than 17 cancer types. Because this analysis shows association rather than direction, both CCDC136-to-partner and partner-to-CCDC136 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by CCDC136-low versus CCDC136-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC136→partner) and Y-score (partner→CCDC136) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.142	+1.326	<.001	<.001	3	18
STOMACH	Heterochromatin formation →	+0.099	+2.079	<.001	<.001	3	17
LUNG_SCLC	Epigenetic regulation of gene expression →	+0.076	+1.566	<.001	<.001	3	17
SOFT_TISSUE	Microtubule organizing center organization →	+0.063	+1.329	<.001	<.001	3	17
OESOPHAGUS	Nuclear export →	+0.119	+2.108	<.001	<.001	3	16
LUNG_SCLC	Heterochromatin organization →	+0.063	+1.222	<.001	.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,063 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by CCDC136 expression — OESOPHAGUS

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