CCDC130

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CCDC130 protein abundance is significantly associated with the RNA expression of many other genes, with 9,280 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CCDC130-associated genes across cancer lineages are BABAM1, AKAP8L, and HAUS8. Each is linked with CCDC130 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCDC130-to-partner and partner-to-CCDC130 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC130 versus BABAM1 in UCEC, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC130→partner) and Y-score (partner→CCDC130) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECBABAM1 →+0.416+0.157.001.00733
OVAKAP8L →+0.553+0.432<.001.00533
GBMHAUS8 →+0.705+0.377<.001<.00133
BRCAANKLE1 →+0.891+0.320<.001.00533
GBMZNF266 →+0.543+0.290<.001<.00133
LSCCZNF101 →+0.366+0.261.003<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,280 associations by consensus.

CCDC130 vs BABAM1 — UCEC

Per-sample scatter of CCDC130 vs BABAM1 in UCEC (Pearson r = 0.30).

Explore this scatter interactively →

Exploration