CCDC130

Across TCGA patient cohorts, CCDC130 mutation is significantly associated with the immune_cell of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC130-associated genes across cancer lineages are GMP, MPP, and CLP. Each is linked with CCDC130 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC130-to-partner and partner-to-CCDC130 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GMP grouped by CCDC130-low versus CCDC130-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC130→partner) and Y-score (partner→CCDC130) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	GMP →	+0.139	+2.416	<.001	.049	3	1
BLCA	MPP →	+0.031	+2.609	.003	.034	3	1
UCEC	CLP →	-0.057	-3.044	.023	<.001	3	1
UCEC	MSC →	-0.177	-1.906	.035	.017	3	1
PRAD	CD8+ T-cells →	+0.039	+5.453	<.001	.044	3	1
UCEC	Smooth muscle →	+0.102	+2.475	.042	.011	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

GMP by CCDC130 expression — BLCA

Explore this box plot interactively →