CCDC130

Across TCGA cell cohorts, CCDC130 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,590 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CCDC130-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and Cilium or flagellum-dependent cell motility. Each is linked with CCDC130 in more than 16 cancer types. Because this analysis shows association rather than direction, both CCDC130-to-partner and partner-to-CCDC130 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by CCDC130-low versus CCDC130-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC130→partner) and Y-score (partner→CCDC130) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.143	+1.127	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.137	+1.004	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.107	-0.723	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Flagellated sperm motility →	-0.118	-0.649	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.107	-0.723	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Cilium movement involved in cell motility →	-0.110	-0.723	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,590 associations by consensus.

Negative regulation of myoblast fusion by CCDC130 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →