CCDC127

Across TCGA pan-cancer cohorts, CCDC127 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CCDC127 data layer compared with 24 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher CCDC127 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated CCDC127 expression acts as an unfavorable survival marker.

CCRCC, PDAC, and HNSC are the cancer types where CCDC127 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	All	0.732	0.937	.002	55	view →
PDAC	DFS	Quartile	All	0.315	0.637	.004	27	view →
HNSC	OS	Median	IV	0.566	0.842	.007	11	view →
LSCC	DFS	Tertile	All	0.328	1.000	.008	10	view →
LUAD	DFS	Median	II,III,IV	0.355	0.663	.030	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CCDC127–CCRCC (OS)

Open the CCRCC breakdown →