CCDC127

Across TCGA patient cohorts, CCDC127 protein abundance is significantly associated with the RNA expression of many other genes, with 14,170 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CCDC127-associated genes across cancer lineages are TPPP, LIFR-AS1, and SMC3. Each is linked with CCDC127 in more than 4 cancer types. Because this analysis shows association rather than direction, both CCDC127-to-partner and partner-to-CCDC127 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC127 versus TPPP in GBM, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC127→partner) and Y-score (partner→CCDC127) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TPPP →	+1.126	+0.227	<.001	.008	3	5
GBM	LIFR-AS1 →	+0.689	+0.367	.001	<.001	3	5
UCEC	SMC3 →	-0.523	-0.321	<.001	<.001	3	4
GBM	LIFR →	+0.962	+0.320	.001	.002	3	4
BRCA	PFDN2 →	-0.925	-0.449	<.001	<.001	3	4
BRCA	LRIG1 →	+0.837	+0.357	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,170 associations by consensus.

CCDC127 vs TPPP — GBM

Explore this scatter interactively →